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Allele Symbol Allele Name Allele ID |
Hdac2tm1Lex targeted mutation 1, Lexicon Genetics MGI:5613704 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice die shortly after birth due to severe cardiac malformation
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• mice die shortly after birth due to severe cardiac malformation
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 7 days following ischemic injury, mice exhibit a less significant decrease in ERG waveforms and reduced loss of retinal thickness with only a slight decrease in the inner plexiform layer and inner nuclear layer thickness compared with wild-type mice
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• 7 days following ischemic injury, mice exhibit a reduced loss of retinal thickness compared with wild-type mice
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• 7 days following ischemic injury, mice exhibit a less significant decrease in ERG waveforms compared with wild-type mice
• however, baseline readings are normal
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• 7 days following ischemic injury, mice exhibit a less significant decrease in ERG waveforms and reduced loss of retinal thickness with only a slight decrease in the inner plexiform layer and inner nuclear layer thickness compared with wild-type mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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