Phenotypes associated with this allele

• Allele Symbol: Rasa1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5609364
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rasa1^tm1b(EUCOMM)Hmgu/Rasa1^tm1b(EUCOMM)Hmgu	C57BL/6N-Rasa1^tm1b(EUCOMM)Hmgu/J	MGI:5767782
ht2	Rasa1^tm1b(EUCOMM)Hmgu/Rasa1^+	C57BL/6N-Rasa1^tm1b(EUCOMM)Hmgu/J	MGI:5797767

Genotype
MGI:5767782

hm1

• Allelic Composition: Rasa1^{tm1b(EUCOMM)Hmgu}/Rasa1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Rasa1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0637_7_H01

Data Sources

IMPC Data for Rasa1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5797767

ht2

• Allelic Composition: Rasa1^{tm1b(EUCOMM)Hmgu}/Rasa1⁺
• Genetic Background: C57BL/6N-Rasa1^{tm1b(EUCOMM)Hmgu}/J
• Cell Lines: HEPD0637_7_H01

Data Sources

IMPC Data for Rasa1

behavior/neurological

abnormal behavior ( J:211773 )

♀

IMPC - JAX

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - JAX

increased heart weight ( J:211773 )

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

IMPC - JAX

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - JAX

thrombocytopenia ( J:211773 )

♀

IMPC - JAX

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♀

IMPC - JAX

decreased circulating phosphate level ( J:211773 )

♀

IMPC - JAX

vision/eye

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - JAX