Phenotypes associated with this allele

• Allele Symbol: Atp6v0d1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5605751
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atp6v0d1^tm1b(EUCOMM)Hmgu/Atp6v0d1^tm1b(EUCOMM)Hmgu	C57BL/6N-Atp6v0d1^tm1b(EUCOMM)Hmgu/Tcp	MGI:5756762
ht2	Atp6v0d1^tm1b(EUCOMM)Hmgu/Atp6v0d1^+	C57BL/6N-Atp6v0d1^tm1b(EUCOMM)Hmgu/Tcp	MGI:5756761

Genotype
MGI:5756762

hm1

• Allelic Composition: Atp6v0d1^{tm1b(EUCOMM)Hmgu}/Atp6v0d1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Atp6v0d1^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0580_4_E01

Data Sources

IMPC Data for Atp6v0d1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - TCP

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - TCP

preweaning lethality, complete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5756761

ht2

• Allelic Composition: Atp6v0d1^{tm1b(EUCOMM)Hmgu}/Atp6v0d1⁺
• Genetic Background: C57BL/6N-Atp6v0d1^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0580_4_E01

Data Sources

IMPC Data for Atp6v0d1

behavior/neurological

increased startle reflex ( J:211773 )

IMPC - TCP

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - TCP

hematopoietic system

decreased mean corpuscular hemoglobin concentration ( J:211773 )

♂

IMPC - TCP

increased neutrophil cell number ( J:211773 )

♂

IMPC - TCP

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - TCP

immune system

increased neutrophil cell number ( J:211773 )

♂

IMPC - TCP

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - TCP

limbs/digits/tail

short tibia ( J:211773 )

♀

IMPC - TCP

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - TCP

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - TCP

skeleton

short tibia ( J:211773 )

♀

IMPC - TCP