Phenotypes associated with this allele

• Allele Symbol: Ywhaz^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:5605747
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ywhaz^tm1b(EUCOMM)Hmgu/Ywhaz^tm1b(EUCOMM)Hmgu	C57BL/6N-Ywhaz^tm1b(EUCOMM)Hmgu/Tcp	MGI:5767849
ht2	Ywhaz^tm1b(EUCOMM)Hmgu/Ywhaz^+	C57BL/6N-Ywhaz^tm1b(EUCOMM)Hmgu/Tcp	MGI:5757900

Genotype
MGI:5767849

hm1

• Allelic Composition: Ywhaz^{tm1b(EUCOMM)Hmgu}/Ywhaz^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Ywhaz^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0716_9_A11

Data Sources

IMPC Data for Ywhaz

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

Genotype
MGI:5757900

ht2

• Allelic Composition: Ywhaz^{tm1b(EUCOMM)Hmgu}/Ywhaz⁺
• Genetic Background: C57BL/6N-Ywhaz^{tm1b(EUCOMM)Hmgu}/Tcp
• Cell Lines: HEPD0716_9_A11

Data Sources

IMPC Data for Ywhaz

cardiovascular system

abnormal sinus arrhythmia ( J:211773 )

IMPC - TCP

hematopoietic system

increased leukocyte cell number ( J:211773 )

♂

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

♂

IMPC - TCP

homeostasis/metabolism

edema ( J:211773 )

IMPC - TCP

immune system

increased leukocyte cell number ( J:211773 )

♂

IMPC - TCP

increased lymphocyte cell number ( J:211773 )

♂

IMPC - TCP

enlarged lymph nodes ( J:211773 )

♂

IMPC - TCP

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - TCP

limbs/digits/tail

short tibia ( J:211773 )

♂

IMPC - TCP

skeleton

short tibia ( J:211773 )

♂

IMPC - TCP

vision/eye

abnormal retina morphology ( J:211773 )

♀

IMPC - TCP