Phenotypes associated with this allele

• Allele Symbol: Adamts3^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5585728
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adamts3^tm1b(KOMP)Wtsi/Adamts3^tm1b(KOMP)Wtsi	C57BL/6N-Adamts3^tm1b(KOMP)Wtsi/Wtsi	MGI:5767556

Genotype
MGI:5767556

hm1

• Allelic Composition: Adamts3^{tm1b(KOMP)Wtsi}/Adamts3^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Adamts3^{tm1b(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0660_2_C10

Data Sources

IMPC Data for Adamts3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

persistent dorsal ophthalmic artery ( J:239583 )

DMDD

persistent trigeminal artery ( J:239583 )

DMDD

aorta coarctation ( J:239583 )

DMDD

absent segment of anterior cerebral artery ( J:239583 )

DMDD

abnormal vertebral artery morphology ( J:239583 )

DMDD

abnormal basilar artery morphology ( J:239583 )

DMDD

abnormal brain artery topology ( J:239583 )

DMDD

absent stapedial artery ( J:239583 )

DMDD

abnormal vitelline vein connection ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal ductus venosus valve morphology ( J:239583 )

DMDD

abnormal ductus venosus valve topology ( J:239583 )

DMDD

absent ductus venosus valve ( J:239583 )

DMDD

dual inferior vena cava ( J:239583 )

DMDD

double outlet right ventricle ( J:239583 )

DMDD

perimembraneous ventricular septal defect ( J:239583 )

DMDD

hemopericardium ( J:239583 )

DMDD

craniofacial

basisphenoid bone foramen ( J:239583 )

DMDD

cleft palate ( J:239583 )

DMDD

digestive/alimentary system

cleft palate ( J:239583 )

DMDD

embryo

abnormal vitelline vein connection ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal Mullerian duct morphology ( J:239583 )

DMDD

abnormal Mullerian duct topology ( J:239583 )

DMDD

abnormal Wolffian duct morphology ( J:239583 )

DMDD

embryo cyst ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal adenohypophysis morphology ( J:239583 )

DMDD

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

growth/size/body

cleft palate ( J:239583 )

DMDD

embryo cyst ( J:239583 )

DMDD

thoracoschisis ( J:239583 )

DMDD

heterochrony ( J:239583 )

DMDD

hearing/vestibular/ear

absent stapedial artery ( J:239583 )

DMDD

homeostasis/metabolism

hemopericardium ( J:239583 )

DMDD

retropleural edema ( J:239583 )

DMDD

subcutaneous edema ( J:239583 )

DMDD

integument

subcutaneous edema ( J:239583 )

DMDD

liver/biliary system

abnormal liver parenchyma morphology ( J:239583 )

DMDD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

neoplasm

increased hemangioma incidence ( J:239583 )

DMDD

increased trigeminal neuroma incidence ( J:239583 )

DMDD

nervous system

absent segment of anterior cerebral artery ( J:239583 )

DMDD

abnormal basilar artery morphology ( J:239583 )

DMDD

abnormal brain artery topology ( J:239583 )

DMDD

increased trigeminal neuroma incidence ( J:239583 )

DMDD

abnormal forebrain morphology ( J:239583 )

DMDD

abnormal adenohypophysis morphology ( J:239583 )

DMDD

multiple persisting craniopharyngeal ducts ( J:239583 )

DMDD

abnormal lateral ventricle morphology ( J:239583 )

DMDD

abnormal third ventricle morphology ( J:239583 )

DMDD

abnormal hindbrain morphology ( J:239583 )

DMDD

abnormal fourth ventricle morphology ( J:239583 )

DMDD

abnormal optic chiasm morphology ( J:239583 )

DMDD

renal/urinary system

bifid ureter ( J:239583 )

DMDD

dilated ureter ( J:239583 )

DMDD

skeleton

basisphenoid bone foramen ( J:239583 )

DMDD

abnormal cervical rib ( J:239583 )

DMDD

fusion of vertebral arches ( J:239583 )

DMDD

vision/eye

abnormal optic chiasm morphology ( J:239583 )

DMDD