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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Akt1tm1Zzy
targeted mutation 1, Zhongzhou Yang
MGI:5563541
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Akt1tm1Zzy/Akt1tm1Zzy
Akt3tm1Hem/Akt3tm1Hem
Tg(Myh6-cre)1Xya/0 		involves: 129P2/OlaHsd * FVB MGI:5563578


Genotype
MGI:5563578
cn1
Allelic
Composition		 Akt1tm1Zzy/Akt1tm1Zzy
Akt3tm1Hem/Akt3tm1Hem
Tg(Myh6-cre)1Xya/0
Genetic
Background		 involves: 129P2/OlaHsd * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Akt1tm1Zzy mutation (0 available); any Akt1 mutation (34 available)
Akt3tm1Hem mutation (0 available); any Akt3 mutation (42 available)
Tg(Myh6-cre)1Xya mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal physiological response to xenobiotic ( J:206783 )
• following myocardial infarction, rapamycin-treated mice exhibit reduced heart weight compared with untreated mice
• however, rapamycin treatment following myocardial infarction fail to exhibit a change in fibrotic index, ejection fraction, fractional shortening or left ventricular internal diameter at end-diastole

cardiovascular system
decreased heart weight ( J:206783 )
• following myocardial infarction, rapamycin-treated mice exhibit reduced heart weight compared with untreated mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory