About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gria1tm7Rlh
targeted mutation 7, Richard L Huganir
MGI:5562310
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gria1tm7Rlh/Gria1tm7Rlh involves: 129S6/SvEvTac * C57BL/6 MGI:5562313


Genotype
MGI:5562313
hm1
Allelic
Composition		 Gria1tm7Rlh/Gria1tm7Rlh
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gria1tm7Rlh mutation (1 available); any Gria1 mutation (62 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:172128 )
N
• mice exhibit normal basal synaptic transmission
abnormal long-term potentiation ( J:172128 )
• long term potentiation induction threshold is reduced compared to in wild-type mice
• mice exhibit long term potentiation induced with spike-timing-dependent plasticity protocols at a long pre-post interval that is subthreshold for wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory