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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ifngr1tm1.2Rds
targeted mutation 1.2, Robert D Schreiber
MGI:5558049
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ifngr1tm1.2Rds/Ifngr1tm1.2Rds C57BL/6NTac-Ifngr1tm1.2Rds MGI:5558058


Genotype
MGI:5558058
hm1
Allelic
Composition
Ifngr1tm1.2Rds/Ifngr1tm1.2Rds
Genetic
Background
C57BL/6NTac-Ifngr1tm1.2Rds
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ifngr1tm1.2Rds mutation (1 available); any Ifngr1 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

immune system
• abrogation of production from CD8a+ dendritic cells of mice infected with L. monocytogenes
• mice infected with L. monocytogenes exhibit increased mortality, spleen and liver bacterial counts and abrogation of IL12b production from CD8a+ dendritic cells compared with wild-type mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory