All Phenotypes Drc1<b2b2237Clo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Drc1^b2b2237Clo
Bench to Bassinet Program (B2B/CVDC), mutation 2237 Cecilia Lo
MGI:5552738

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Drc1^b2b2237Clo/Drc1^b2b2237Clo	C57BL/6J-Drc1^b2b2237Clo	MGI:5554187

Allelic Composition	Drc1^b2b2237Clo/Drc1^b2b2237Clo
Genetic Background	C57BL/6J-Drc1^b2b2237Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Drc1^b2b2237Clo mutation (1 available); any Drc1 mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 2237-004-NA shows situs inversus totalis with dextrocardia, inverted outflow, inverted lung and liver lobation, dextrogastria as well as biventricular hypertrophy that was confirmed by EFIC imaging

cardiovascular system

dextrocardia ( J:175213 )

growth/size/body

abdominal situs inversus ( J:175213 )

situs inversus totalis ( J:175213 )

Mouse Models of Human Disease	DO ID	OMIM ID(s)	Ref(s)
Kartagener syndrome	DOID:0050144		J:175213
primary ciliary dyskinesia 21	DOID:0110596	OMIM:615294	J:175213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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