All Phenotypes Gnao1<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gnao1^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5548941

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gnao1^{tm1b(EUCOMM)Hmgu}/Gnao1^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Gnao1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757181
ht2	Gnao1^{tm1b(EUCOMM)Hmgu}/Gnao1⁺	C57BL/6N-Gnao1^{tm1b(EUCOMM)Hmgu}/H	MGI:5757180

Allelic Composition	Gnao1^{tm1b(EUCOMM)Hmgu}/Gnao1^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Gnao1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0618_2_G05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gnao1^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Gnao1 mutation (29 available)

Data Sources

IMPC Data for Gnao1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Gnao1^{tm1b(EUCOMM)Hmgu}/Gnao1⁺
Genetic Background	C57BL/6N-Gnao1^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0618_2_G05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gnao1^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Gnao1 mutation (29 available)

Data Sources

IMPC Data for Gnao1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

decreased anxiety-related response ( J:211773 )

IMPC - HAR

impaired righting response ( J:211773 )

IMPC - HAR

hyperactivity ( J:211773 )

IMPC - HAR

hematopoietic system

decreased eosinophil cell number ( J:211773 )

IMPC - HAR

decreased erythrocyte cell number ( J:211773 )

IMPC - HAR

increased mean corpuscular hemoglobin ( J:211773 )

IMPC - HAR

decreased red blood cell distribution width ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating creatinine level ( J:211773 )

IMPC - HAR

increased blood urea nitrogen level ( J:211773 )

IMPC - HAR

decreased fasting circulating glucose level ( J:211773 )

IMPC - HAR

increased circulating triglyceride level ( J:211773 )

IMPC - HAR

decreased circulating iron level ( J:211773 )

IMPC - HAR

increased circulating amylase level ( J:211773 )

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

IMPC - HAR

decreased respiratory quotient ( J:211773 )

IMPC - HAR

immune system

decreased eosinophil cell number ( J:211773 )

IMPC - HAR

skeleton

abnormal bone structure ( J:211773 )

IMPC - HAR

decreased bone mineral content ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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