All Phenotypes Klf7<tm1b(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Klf7^{tm1b(EUCOMM)Hmgu}
targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
MGI:5548730

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Klf7^{tm1b(EUCOMM)Hmgu}/Klf7^{tm1b(EUCOMM)Hmgu}	C57BL/6N-Klf7^{tm1b(EUCOMM)Hmgu}/H	MGI:5757288
ht2	Klf7^{tm1b(EUCOMM)Hmgu}/Klf7⁺	C57BL/6N-Klf7^{tm1b(EUCOMM)Hmgu}/H	MGI:5757287

Allelic Composition	Klf7^{tm1b(EUCOMM)Hmgu}/Klf7^{tm1b(EUCOMM)Hmgu}
Genetic Background	C57BL/6N-Klf7^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0554_3_F09

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klf7^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Klf7 mutation (21 available)

Data Sources

IMPC Data for Klf7

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Klf7^{tm1b(EUCOMM)Hmgu}/Klf7⁺
Genetic Background	C57BL/6N-Klf7^{tm1b(EUCOMM)Hmgu}/H
Cell Lines	HEPD0554_3_F09

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klf7^{tm1b(EUCOMM)Hmgu} mutation (0 available); any Klf7 mutation (21 available)

Data Sources

IMPC Data for Klf7

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired righting response ( J:211773 )

IMPC - HAR

hyperactivity ( J:211773 )

IMPC - HAR

hematopoietic system

increased mean platelet volume ( J:211773 )

IMPC - HAR

homeostasis/metabolism

increased circulating aspartate transaminase level ( J:211773 )

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

IMPC - HAR

skeleton

abnormal vertebrae morphology ( J:211773 )

IMPC - HAR

vision/eye

persistence of hyaloid vascular system ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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