Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1Mro mutation
(1 available);
any
Pten mutation
(81 available)
Sdhbtm1.1Ics mutation
(0 available);
any
Sdhb mutation
(27 available)
Sdhbtm1.2Ics mutation
(0 available);
any
Sdhb mutation
(27 available)
Tg(KLK3-cre)D4Trp mutation
(0 available)
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endocrine/exocrine glands
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• 42% incidence of pheochromocytoma
• tumors do not show accumulation of succinate
|
neoplasm
|
• 42% incidence of pheochromocytoma
• tumors do not show accumulation of succinate
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sdhbtm1.1Ics mutation
(0 available);
any
Sdhb mutation
(27 available)
Tg(Th-cre)12Mrub mutation
(0 available)
|
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normal phenotype
|
• mice are viable, fertile and have no apparent phenotype
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sdhbtm1.1Ics mutation
(0 available);
any
Sdhb mutation
(27 available)
Tg(KLK3-cre)D4Trp mutation
(0 available)
|
|
|
normal phenotype
|
• mice are viable, fertile and have no apparent phenotype
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1Mro mutation
(1 available);
any
Pten mutation
(81 available)
Sdhbtm1.1Ics mutation
(0 available);
any
Sdhb mutation
(27 available)
Tg(KLK3-cre)D4Trp mutation
(0 available)
|
|
|
endocrine/exocrine glands
|
• 89% of mice show pheochromocytoma at 12.9 months of age
• tumors do not show accumulation of succinate
|
neoplasm
|
• 89% of mice show pheochromocytoma at 12.9 months of age
• tumors do not show accumulation of succinate
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1Mro mutation
(1 available);
any
Pten mutation
(81 available)
Sdhbtm1.1Ics mutation
(0 available);
any
Sdhb mutation
(27 available)
Tg(KLK3-cre)D4Trp mutation
(0 available)
|
|
|
endocrine/exocrine glands
|
• 64% of mice develop pheochromocytoma
|
neoplasm
|
• 64% of mice develop pheochromocytoma
|