Phenotypes associated with this allele

• Allele Symbol: Creb3l3^tm1Ktak
• Allele Name: targeted mutation 1, Kiyoshi Takeda
• Allele ID: MGI:5502394
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Creb3l3^tm1Ktak/Creb3l3^tm1Ktak	involves: 129S4/SvJae * C57BL/6	MGI:5502397

Genotype
MGI:5502397

hm1

• Allelic Composition: Creb3l3^tm1Ktak/Creb3l3^tm1Ktak
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:197204 )

• mice exhibit resistance to sulpyrine-induced shock compared with wild-type mice

• however, response to acetaminophen is normal

homeostasis/metabolism

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:197204 )

• mice exhibit resistance to sulpyrine-induced shock compared with wild-type mice

• however, response to acetaminophen is normal

decreased physiological sensitivity to xenobiotic ( J:197204 )

• mice exhibit resistance to sulpyrine-induced shock with a more gradual decrease in body temperature and decreased serum levels of sulpyrine metabolite 4-AA compared with wild-type mice

• however, response to acetaminophen is normal