Phenotypes associated with this allele

• Allele Symbol: Bbs1^tm2Vcs
• Allele Name: targeted mutation 2, Val C Sheffield
• Allele ID: MGI:5474481
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Bbs1^tm2Vcs/Bbs1^tm2Vcs Tg(Pdgfra-cre)1Clc/0	involves: 129S6/SvEvTac * C57BL/6	MGI:5474570

Genotype
MGI:5474570

cn1

• Allelic Composition: Bbs1^tm2Vcs/Bbs1^tm2Vcs; Tg(Pdgfra-cre)1Clc/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:194096 )

N • motile cilia in the lateral ventricles are normal

increased neuron apoptosis ( J:194096 )

• 2-fold

decreased neuronal precursor proliferation ( J:194096 )

• reduced 50%

hydrocephaly ( J:194096 )

• non-obstructive beginning at P3

cellular

increased neuron apoptosis ( J:194096 )

• 2-fold

decreased neuronal precursor proliferation ( J:194096 )

• reduced 50%

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Bardet-Biedl syndrome 1		DOID:0110123	OMIM:209900	J:194096