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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Foxn1nu-2J
nude 2 Jackson
MGI:5464997
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Foxn1nu-2J/Foxn1nu-2J B6(SJL)-Foxn1nu-2J/GrsrJ MGI:5465030


Genotype
MGI:5465030
hm1
Allelic
Composition
Foxn1nu-2J/Foxn1nu-2J
Genetic
Background
B6(SJL)-Foxn1nu-2J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxn1nu-2J mutation (1 available); any Foxn1 mutation (97 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system

immune system

integument
• hair does not grown in and mice remain essentially hairless throughout life
• microscopic examination of plucks of the little hair available showed there to be clumps of tangled, broken hairs indicative of fragile hair
• severe follicular dystrophy with clumping, broken hair in histological section at 8 weeks of age
• vibrissae of homozygotes may be sparse, short and curled, or absent
• wrinkled skin evident by approximately 1 week of age

reproductive system
• female homozygotes may bear no live pups or have small litter sizes

mortality/aging
• many homozygotes do not survive to wean age, although some do and survive to breed

growth/size/body

hearing/vestibular/ear
• hearing impairment at higher frequencies was found by ABR testing of 2 male homozygotes at 6 weeks of age

endocrine/exocrine glands





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory