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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nlrc4tm1Gne
targeted mutation 1, Genentech
MGI:5446022
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nlrc4tm1Gne/Nlrc4tm1Gne involves: C57BL/6N MGI:5446023


Genotype
MGI:5446023
hm1
Allelic
Composition		 Nlrc4tm1Gne/Nlrc4tm1Gne
Genetic
Background		 involves: C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrc4tm1Gne mutation (0 available); any Nlrc4 mutation (67 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:189256 )
N
• bone marrow-derived macrophages exhibit normal processing of Caspase 1 and secretion of IL1b following infection with S. typhimurium




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory