Phenotypes associated with this allele

• Allele Symbol: Tmeff2^tm1Fawa
• Allele Name: targeted mutation 1, Fan Wang
• Allele ID: MGI:5438565
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmeff2^tm1Fawa/Tmeff2^tm1Fawa	involves: 129P2/OlaHsd	MGI:5438566
ht2	Tmeff2^tm1Fawa/Tmeff2^+	involves: 129P2/OlaHsd	MGI:5438567

Genotype
MGI:5438566

hm1

• Allelic Composition: Tmeff2^tm1Fawa/Tmeff2^tm1Fawa
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality at weaning, complete penetrance ( J:187163 )

• all die around weaning age

growth/size/body

decreased body size ( J:187163 )

slow postnatal weight gain ( J:187163 )

adipose tissue

decreased white adipose tissue amount ( J:187163 )

nervous system

nervous system phenotype ( J:187163 )

N • neuron differentiation is normal and no abnormalities are detected in the brain or spinal cord

reproductive system

reproductive system phenotype ( J:187163 )

♂N • no defects are detected in the prostate gland

neoplasm

neoplasm ( J:187163 )

N • despite a potential role as a tumor suppressor, no tumors are detected

Genotype
MGI:5438567

ht2

• Allelic Composition: Tmeff2^tm1Fawa/Tmeff2⁺
• Genetic Background: involves: 129P2/OlaHsd

neoplasm

neoplasm ( J:187163 )

N • despite a potential role as a tumor suppressor, no tumors are detected