Phenotypes associated with this allele

• Allele Symbol: Tab1^b2b449Clo
• Allele Name: Bench to Bassinet Program (B2B/CVDC), mutation 449 Cecilia Lo
• Allele ID: MGI:5314079
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tab1^b2b449Clo/Tab1^b2b449Clo	C57BL/6J-Tab1^b2b449Clo	MGI:5314080

Genotype
MGI:5314080

hm1

• Allelic Composition: Tab1^b2b449Clo/Tab1^b2b449Clo
• Genetic Background: C57BL/6J-Tab1^b2b449Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 449-005-1 (E16.5) exhibit interrupted aortic arch (IAA) and malalignment of the great arteries, which was shown to be double outlet right ventricle (DORV) by EFIC analysis.

cardiovascular system

abnormal aortic arch morphology ( J:175213 )

• hypoplastic transverse arch, transverse arch obstruction, interrupted aortic arch and vascular sling

aortic arch obstruction ( J:175213 )

• transverse arch obstruction

interrupted aortic arch, type b ( J:175213 )

• interrupted aortic arch type b

persistent truncus arteriosus type ii ( J:175213 )

• truncus arteriosus type ii

double outlet right ventricle ( J:175213 )

overriding aortic valve ( J:175213 )

ventricular septal defect ( J:175213 )