Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2d mutation
(23 available);
any
H2 mutation
(280 available)
Trap1atm1.1Jvde mutation
(0 available);
any
Trap1a mutation
(7 available)
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reproductive system
N |
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2d mutation
(23 available);
any
H2 mutation
(280 available)
Trap1atm1.1Jvde mutation
(0 available);
any
Trap1a mutation
(7 available)
|
|
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mortality/aging
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• mice exhibit spontaneous rejection of P815 tumors and increased survival compared with wild-type mice
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reproductive system
N |
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immune system
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• P1A35-43-specific CD8 T lymphocytes exhibit increased functional avidity compared with wild-type cells
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• mice exhibit increased immunogenic response towards P1A35-43 compared with wild-type mice
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neoplasm
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• mice exhibit spontaneous rejection of P815 tumors and increased survival compared with wild-type mice
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hematopoietic system
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• P1A35-43-specific CD8 T lymphocytes exhibit increased functional avidity compared with wild-type cells
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2d mutation
(23 available);
any
H2 mutation
(280 available)
Tg(TcraP1.5,TcrbP1.5)29Amsv mutation
(0 available)
Trap1atm1.1Jvde mutation
(0 available);
any
Trap1a mutation
(7 available)
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immune system
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• T lymphocytes expressing the transgene are negatively selected in the thymus and strongly reduced in the periphery
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hematopoietic system
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• T lymphocytes expressing the transgene are negatively selected in the thymus and strongly reduced in the periphery
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