Mouse Genome Informatics
tg1
    Tg(Thy1-GLRA1*R271Q)382Wha/Tg(Thy1-GLRA1*R271Q)382Wha
involves: C57BL/6 * DBA/2
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
behavior/neurological
• onset at ~2 weeks of age
• onset at ~2 weeks of age
• clench hind feet when lifted by the tail from ~2 weeks of age
• exhibit spontaneous and handling-induced 25-30 Hz tremors with onset at ~2 weeks of age

Mouse Models of Human Disease
OMIM IDRef(s)
Hyperekplexia, Hereditary 1; HKPX1 149400 J:76009


Mouse Genome Informatics
tg2
    Tg(Thy1-GLRA1*R271Q)382Wha/0
involves: C57BL/6 * DBA/2
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
normal phenotype
• in contrast with mice hemizygous for Tg(Thy1-GLRA1*R271Q)300Wha, hemizygotes for the present transgene exhibit no overt abnormalities