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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Thy1-GLRA1*R271Q)382Wha
transgene insertion 382, Hans Weiher
MGI:5306914
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Thy1-GLRA1*R271Q)382Wha/Tg(Thy1-GLRA1*R271Q)382Wha involves: C57BL/6 * DBA/2 MGI:5306916
tg2
Tg(Thy1-GLRA1*R271Q)382Wha/0 involves: C57BL/6 * DBA/2 MGI:5306915


Genotype
MGI:5306916
tg1
Allelic
Composition
Tg(Thy1-GLRA1*R271Q)382Wha/Tg(Thy1-GLRA1*R271Q)382Wha
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• onset at ~2 weeks of age
• onset at ~2 weeks of age
• clench hind feet when lifted by the tail from ~2 weeks of age
• exhibit spontaneous and handling-induced 25-30 Hz tremors with onset at ~2 weeks of age

Mouse Models of Human Disease
OMIM ID Ref(s)
Hyperekplexia, Hereditary 1; HKPX1 149400 J:76009




Genotype
MGI:5306915
tg2
Allelic
Composition
Tg(Thy1-GLRA1*R271Q)382Wha/0
Genetic
Background
involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• in contrast with mice hemizygous for Tg(Thy1-GLRA1*R271Q)300Wha, hemizygotes for the present transgene exhibit no overt abnormalities





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory