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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sirt5tm1.1Ics
targeted mutation 1.1, Mouse Clinical Institute
MGI:5297911
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sirt5tm1.1Ics/Sirt5tm1.1Ics Not Specified MGI:5297913


Genotype
MGI:5297913
hm1
Allelic
Composition		 Sirt5tm1.1Ics/Sirt5tm1.1Ics
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sirt5tm1.1Ics mutation (1 available); any Sirt5 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal homeostasis ( J:177830 )
• succinylation levels on lys1291 of Cps1 are increased compared to in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory