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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(CD4-Il17re)#Cdon
transgene insertion, Chen Dong
MGI:5297501
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(CD4-Il17re)#Cdon/0 involves: C57BL/6 MGI:5297502


Genotype
MGI:5297502
tg1
Allelic
Composition		 Tg(CD4-Il17re)#Cdon/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(CD4-Il17re)#Cdon mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal interleukin secretion ( J:177650 )
• MOG35-55-stimulated splenocytes exhibit decreased IL17A, IL17F, and IL22 production compared with similarly treated wild-type cells
decreased interleukin-17 secretion ( J:177650 )
• MOG35-55-stimulated splenocytes exhibit decreased IL17A and IL17F production compared with similarly treated wild-type cells
increased susceptibility to experimental autoimmune encephalomyelitis ( J:177650 )
• with exacerbated symptoms and increased production of IL17A, IL17F, and IL22




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory