About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pbktm1Zgdo
targeted mutation 1, Zigang Dong
MGI:5293435
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Pbktm1Zgdo/Pbktm1Zgdo Not Specified MGI:5294464


Genotype
MGI:5294464
hm1
Allelic
Composition
Pbktm1Zgdo/Pbktm1Zgdo
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pbktm1Zgdo mutation (0 available); any Pbk mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• UV-exposed mice exhibit increased deposition of the extracellular matrix unlike in similarly treated wild-type mice
• UV-exposed mice lose most of the horny layers of the epidermic compared with similarly treated wild-type mice
• in UV-treated mice
• moderate in UV-treated mice

immune system
• LPS-stimulated mouse embryonic fibroblasts produce less IL6 compared with similarly treated wild-type cells
• mouse embryonic fibroblasts exposed to solar UV radiation
• mouse embryonic fibroblasts exposed to solar UV radiation





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory