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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Mapt-MAPT*)#Hanr
transgene insertion, Hanna Rosenmann
MGI:5052111
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Mapt-MAPT*)#Hanr/0 involves: BALB/c * C57BL/6 MGI:5052112


Genotype
MGI:5052112
tg1
Allelic
Composition
Tg(Mapt-MAPT*)#Hanr/0
Genetic
Background
involves: BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• plaque like structures are detected but no amyloid beta protein is detected in these plaques (J:137947)
• plaque like structures are detected but no amyloid beta protein is detected in these plaques (J:137947)
• are detected in the cortex, hippocampus and brainstem at 6 months of age and to a greater extent at 9 months of age (J:137947)
• are detected in the cortex, hippocampus and brainstem at 6 months of age and to a greater extent at 9 months of age (J:137947)
• at 10 months of age (J:137947)
• at 10 months of age (J:137947)
• in the cortex, hippocampus and brainstem at 6 months of age and to a greater extent at 9 months of age (J:137947)
• in the cortex, hippocampus and brainstem at 6 months of age and to a greater extent at 9 months of age (J:137947)
• able to induce short term potentiation but unable to maintain it (J:137947)
• able to induce short term potentiation but unable to maintain it (J:137947)
• at 60 ms inter-stimulus intervals (J:137947)
• at 60 ms inter-stimulus intervals (J:137947)

behavior/neurological
N
• do not display any gross motor defects (J:137947)
• do not display any gross motor defects (J:137947)
• defecate and urinate excessively in an 8 arm maze suggesting an increase in anxiety (J:137947)
• defecate and urinate excessively in an 8 arm maze suggesting an increase in anxiety (J:137947)
• at 6-7 months of age, perform worse in an 8 arm maze over 5 days of training (J:137947)
• deficits remain at 9 months of age (J:137947)
• at 6-7 months of age, perform worse in an 8 arm maze over 5 days of training (J:137947)
• deficits remain at 9 months of age (J:137947)
• at 6-7 months of age, perform worse in an 8 arm maze over 5 days of training (J:137947)
• deficits remain at 9 months of age (J:137947)
• at 6-7 months of age, perform worse in an 8 arm maze over 5 days of training (J:137947)
• deficits remain at 9 months of age (J:137947)

Mouse Models of Human Disease
OMIM ID Ref(s)
Alzheimer Disease; AD 104300 J:137947





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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory