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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		9430015G10Riktm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007003
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		9430015G10Riktm1Lex/9430015G10Riktm1Lex B6;129S5-9430015G10Riktm1Lex/Mmucd MGI:5827985


Genotype
MGI:5827985
hm1
Allelic
Composition		 9430015G10Riktm1Lex/9430015G10Riktm1Lex
Genetic
Background		 B6;129S5-9430015G10Riktm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
9430015G10Riktm1Lex mutation (2 available); any 9430015G10Rik mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased thermal nociceptive threshold ( J:171883 )
• decreased sensitivity to acute pain during hot plate testing

hematopoietic system
increased B cell number ( J:171883 )
• increased mean percentage of B cells in peripheral blood
decreased CD4-positive, alpha-beta T cell number ( J:171883 )
• decreased mean percentage of CD4 cells in peripheral blood

immune system
increased B cell number ( J:171883 )
• increased mean percentage of B cells in peripheral blood
decreased CD4-positive, alpha-beta T cell number ( J:171883 )
• decreased mean percentage of CD4 cells in peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory