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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Clmptm1Lex
targeted mutation 1, Lexicon Pharmaceuticals
MGI:5007002
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Clmptm1Lex/Clmptm1Lex B6;129S5-Clmptm1Lex/Mmucd MGI:5827982


Genotype
MGI:5827982
hm1
Allelic
Composition
Clmptm1Lex/Clmptm1Lex
Genetic
Background
B6;129S5-Clmptm1Lex/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clmptm1Lex mutation (1 available); any Clmp mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• exhibited numerous neurological abnormalities

renal/urinary system
• both CAT-Scan analysis and necropsy revealed bilateral hydronephrosis in surviving homozygous mutant mice

cardiovascular system
• notably increased mean systolic blood pressure

mortality/aging
N
• this mutation resulted in reduced viability of the homozygous mutants

growth/size/body
• mutants were smaller than controls

homeostasis/metabolism
• exhibited numerous blood chemistry abnormalities





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory