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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo
transgene insertion 110, David R Borchelt
MGI:4849838
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo/Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo involves: C3H * C57BL/6 MGI:4849842


Genotype
MGI:4849842
tg1
Allelic
Composition
Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo/Tg(Prnp-SOD1*G37R,-PSEN1)110Dbo
Genetic
Background
involves: C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• by 7 to 9 months, mice develop motor neuron disease that progresses rapidly unlike wild-type mice

behavior/neurological
• within 1 to 3 weeks of visible gait disturbance

Mouse Models of Human Disease
OMIM ID Ref(s)
Amyotrophic Lateral Sclerosis 1; ALS1 105400 J:104655





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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory