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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
avc4
atrioventricular canal 4
MGI:4821828
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
avc4/avc4 involves: C57BL/6J * FVB/N MGI:4822145


Genotype
MGI:4822145
hm1
Allelic
Composition
avc4/avc4
Genetic
Background
involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• 2 of 25 mice exhibit hypoplastic pulmonary artery
• 3 of 25 mice exhibit interrupted aortic arch
• some mutant mice develop atrial septal defects of the primum type
• all mice exhibit septal defects with expressivity varying from primum atrial septal defect to complete AVSD
• some mutant mice develop atrioventricular septal defects of the complete common atrioventricular canal type
• approximately half of affected mutants exhibit unbalanced hypoplastic right ventricle

Mouse Models of Human Disease
OMIM ID Ref(s)
Atrioventricular Septal Defect; AVSD 606215 J:163196





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory