Mouse Genome Informatics
hm1
     avc3/avc3
involves: C57BL/6J * FVB/N
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
mortality/aging
partial embryonic lethality ( J:163196 )
• at E14, 30% of mutants exhibit embryonic lethality

cardiovascular system
abnormal myocardium compact layer morphology ( J:163196 )
• mutant mice exhibit diminished compact myocardium
complete atrioventricular septal defect ( J:163196 )
• mutant mice develop atrioventricular septal defects of the complete common atrioventricular canal type

Mouse Models of Human Disease
 OMIM IDRef(s)
Atrioventricular Septal Defect; AVSD 606215 J:163196