Mouse Genome Informatics
hm1
     avc2/avc2
involves: C57BL/6J * FVB/N
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
mortality/aging

cardiovascular system
ostium primum atrial septal defect ( J:163196 )
• each mutant mouse displayed an incomplete AVSD (an atrial septal defect of the primum type)
• Background Sensitivity: the phenotype is incompletely penetrant was lost after repeated outcrossing to FVB; however, the phenotype was re-established after a two-generation backcross to a C57BL/6-A/J chromosome 15 chromosome substitution strain (C57BL/6J-Chr15A/NaJ)

limbs/digits/tail
preaxial polydactyly ( J:163196 )
• observed on all limbs

Mouse Models of Human Disease
 OMIM IDRef(s)
Atrial Septal Defect 1; ASD1 108800 J:163196