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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Tnnt2-TNNT2*R92Q)#Ajm
transgene insertion, Ali J Marian
MGI:4819718
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Tnnt2-TNNT2*R92Q)#Ajm/0 involves: C3H * C57BL/6 * ICR MGI:4819725


Genotype
MGI:4819725
tg1
Allelic
Composition
Tg(Tnnt2-TNNT2*R92Q)#Ajm/0
Genetic
Background
involves: C3H * C57BL/6 * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• cardiomyocyte disarray
• increase in interstitial collagen
• the decrease in the ratio of peak early velocity to peak atrial velocity is indicative of left ventricular diastolic dysfunction
• increase in mitral valve peak atrial velocity and a decrease in the ratio of peak early velocity to peak atrial velocity compared to controls

muscle
• cardiomyocyte disarray

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
hypertrophic cardiomyopathy 2 DOID:0110308 OMIM:115195
J:117554





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory