Phenotypes associated with this allele

• Allele Symbol: Nr4a3^tm1Dgen
• Allele Name: targeted mutation 1, Deltagen
• Allele ID: MGI:4819522
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Nr4a2^tm1Tpe/Nr4a2^+ Nr4a3^tm1Dgen/Nr4a3^tm1Dgen	involves: 129P2/OlaHsd	MGI:4820560

Genotype
MGI:4820560

cx1

• Allelic Composition: Nr4a2^tm1Tpe/Nr4a2⁺; Nr4a3^tm1Dgen/Nr4a3^tm1Dgen
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

increased susceptibility to neuronal excitotoxicity ( J:162076 )

• kainic-acid treated mice exhibit decreased cell density in the CA1 hippocampus with evidence of increased oxidative stress compared with similarly treated wild-type mice

cellular

increased susceptibility to neuronal excitotoxicity ( J:162076 )

• kainic-acid treated mice exhibit decreased cell density in the CA1 hippocampus with evidence of increased oxidative stress compared with similarly treated wild-type mice

oxidative stress ( J:162076 )

• kainic-acid treated mice exhibit decreased cell density in the CA1 hippocampus with evidence of increased oxidative stress compared with similarly treated wild-type mice

homeostasis/metabolism

increased susceptibility to neuronal excitotoxicity ( J:162076 )

• kainic-acid treated mice exhibit decreased cell density in the CA1 hippocampus with evidence of increased oxidative stress compared with similarly treated wild-type mice