All Phenotypes Itga5<tm2.1Hyn> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Itga5^tm2.1Hyn
targeted mutation 2.1, Richard Hynes
MGI:4818933

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Itga5^tm2.1Hyn/Itga5^tm2.1Hyn	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	MGI:4818934

Allelic Composition	Itga5^tm2.1Hyn/Itga5^tm2.1Hyn
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itga5^tm2.1Hyn mutation (0 available); any Itga5 mutation (45 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• die around E11

embryo

embryonic growth retardation ( J:161850 )

• embryos at E10.5 are severely growth retarded

incomplete somite formation ( J:161850 )

• posterior somites

growth/size/body

embryonic growth retardation ( J:161850 )

• embryos at E10.5 are severely growth retarded

cardiovascular system

abnormal blood vessel morphology ( J:161850 )

• reduced vascularization

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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