All Phenotypes Slc15a1<tm1Dgen> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Slc15a1^tm1Dgen
targeted mutation 1, Deltagen
MGI:4818784

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc15a1^tm1Dgen/Slc15a1^tm1Dgen	involves: 129P2/OlaHsd * C57BL/6	MGI:4818785

Allelic Composition	Slc15a1^tm1Dgen/Slc15a1^tm1Dgen
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc15a1^tm1Dgen mutation (1 available); any Slc15a1 mutation (41 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

digestive/alimentary system

abnormal intestinal absorption ( J:162297 )

• glycylsarcosine uptake by everted jejunal rings is only 22% of controls

• peptide permeability is only 5% of controls in whole animal studies

• peak circulating concentrations of glycylsarcosine are substantially reduced relative to controls after gastric lavage

• mice otherwise display a normal phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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