All Phenotypes Ripply1<tm1.1Sjt> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ripply1^tm1.1Sjt
targeted mutation 1.1, Shinji Takada
MGI:4459309

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ripply1^tm1.1Sjt/Ripply1^tm1.1Sjt	involves: 129S1/Sv * FVB/N	MGI:4459312
cx2	Ripply1^tm1.1Sjt/Ripply1^tm1.1Sjt Ripply2^tm1.1Ysa/Ripply2^tm1.1Ysa	involves: 129S1/Sv * C57BL/6 * CBA * FVB/N	MGI:4459313
cx3	Ripply1^tm1.1Sjt/Y Ripply2^tm1.1Ysa/Ripply2^tm1.1Ysa	involves: 129S1/Sv * C57BL/6 * CBA * FVB/N	MGI:4459314
ot4	Ripply1^tm1.1Sjt/Y	involves: 129S1/Sv * FVB/N	MGI:4459311

Allelic Composition	Ripply1^tm1.1Sjt/Ripply1^tm1.1Sjt
Genetic Background	involves: 129S1/Sv * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ripply1^tm1.1Sjt mutation (0 available); any Ripply1 mutation (9 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal cervical vertebrae morphology ( J:161418 )

• some mice exhibit an extension of the seventh cervical vertebra that fuses to the first rib unlike in wild-type mice

Allelic Composition	Ripply1^tm1.1Sjt/Ripply1^tm1.1Sjt Ripply2^tm1.1Ysa/Ripply2^tm1.1Ysa
Genetic Background	involves: 129S1/Sv * C57BL/6 * CBA * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ripply1^tm1.1Sjt mutation (0 available); any Ripply1 mutation (9 available)
Ripply2^tm1.1Ysa mutation (1 available); any Ripply2 mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal vertebrae morphology ( J:161418 )

• mice exhibit rostralization of vertebrae compared with wild-type mice that is enhanced compared to in Ripply2^tm1.1Ysa homozygotes

absent vertebral pedicles ( J:161418 )

• with fusion of the lamina in the vertebrae

embryo

abnormal rostral-caudal patterning of the somites ( J:161418 )

• marker expression reveals rostralization of somites compared to in wild-type mice

Allelic Composition	Ripply1^tm1.1Sjt/Y Ripply2^tm1.1Ysa/Ripply2^tm1.1Ysa
Genetic Background	involves: 129S1/Sv * C57BL/6 * CBA * FVB/N

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal vertebrae morphology ( J:161418 )

• mice exhibit rostralization of vertebrae compared with wild-type mice that is enhanced compared to in Ripply2^tm1.1Ysa homozygotes

absent vertebral pedicles ( J:161418 )

• with fusion of the lamina in the vertebrae

embryo

abnormal rostral-caudal patterning of the somites ( J:161418 )

• marker expression reveals rostralization of somites compared to in wild-type mice

Allelic Composition	Ripply1^tm1.1Sjt/Y
Genetic Background	involves: 129S1/Sv * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ripply1^tm1.1Sjt mutation (0 available); any Ripply1 mutation (9 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal cervical vertebrae morphology ( J:161418 )

• some mice exhibit an extension of the seventh cervical vertebra that fuses to the first rib unlike in wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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