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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Uchl1gad-2J
gracile axonal dystrophy 2 Jackson
MGI:4458326
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Uchl1gad-2J/Uchl1gad-2J B6.Cg-Uchl1gad-2J/GrsrJ MGI:4460998


Genotype
MGI:4460998
hm1
Allelic
Composition
Uchl1gad-2J/Uchl1gad-2J
Genetic
Background
B6.Cg-Uchl1gad-2J/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Uchl1gad-2J mutation (1 available); any Uchl1 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

behavior/neurological
• at 6 or 7 weeks of age the hind legs begin to show weakness characterized by limb grasping, dragging or splaying when walking
• loss of hind limb function progresses to paralysis and premature death

growth/size/body
• a progressive loss in body weight begins at 12 weeks of age

nervous system
• one mouse at 21 weeks of age was assessed and found to have degeneration of long tracks in the spinal cord and extensive neurogenic atrophy in the hind leg





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory