All Phenotypes Tmem204<tm1.1Ali> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tmem204^tm1.1Ali
targeted mutation 1.1, Kari Alitalo
MGI:4454669

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem204^tm1.1Ali/Tmem204^tm1.1Ali	involves: BALB/c * C57BL/6	MGI:4454671
cx2	Kdr^tm1Jrt/Kdr⁺ Tmem204^tm1.1Ali/Tmem204^tm1.1Ali	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	MGI:4454673
cx3	Flt4^tm1Ali/Flt4⁺ Tmem204^tm1.1Ali/Tmem204^tm1.1Ali	involves: BALB/c * C57BL/6	MGI:4454672

Allelic Composition	Tmem204^tm1.1Ali/Tmem204^tm1.1Ali
Genetic Background	involves: BALB/c * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmem204^tm1.1Ali mutation (0 available); any Tmem204 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal lymphatic vessel smooth muscle morphology ( J:159519 )

• the enlarged initial lymphatic vessels has an increased number of associated smooth muscle cells when compared with wild-type

• enlarged lymphatic vessels in various organ with abnormal smooth muscle cell coating

enlarged lymphatic vessel ( J:159519 )

• enlarged lymphatic vessels in various organ with abnormal smooth muscle cell coating

• collecting lymphatic vessels located in the deeper layers of the ears of the mice are dilated

• the enlarged initial lymphatic vessels has an increased number of associated smooth muscle cells when compared with wild-type

muscle

abnormal lymphatic vessel smooth muscle morphology ( J:159519 )

• the enlarged initial lymphatic vessels has an increased number of associated smooth muscle cells when compared with wild-type

• enlarged lymphatic vessels in various organ with abnormal smooth muscle cell coating

Allelic Composition	Kdr^tm1Jrt/Kdr⁺ Tmem204^tm1.1Ali/Tmem204^tm1.1Ali
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdr^tm1Jrt mutation (1 available); any Kdr mutation (71 available)
Tmem204^tm1.1Ali mutation (0 available); any Tmem204 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal lymphatic vessel smooth muscle morphology ( J:159519 )

• abnormal smooth muscle cell coating

enlarged lymphatic vessel ( J:159519 )

• enlarged lymphatic vessels are even more dilated than in Tmem204^tm1.1Ali single knock-outs

muscle

abnormal lymphatic vessel smooth muscle morphology ( J:159519 )

• abnormal smooth muscle cell coating

Allelic Composition	Flt4^tm1Ali/Flt4⁺ Tmem204^tm1.1Ali/Tmem204^tm1.1Ali
Genetic Background	involves: BALB/c * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Flt4^tm1Ali mutation (1 available); any Flt4 mutation (76 available)
Tmem204^tm1.1Ali mutation (0 available); any Tmem204 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal lymphatic vessel smooth muscle morphology ( J:159519 )

• abnormal smooth muscle cell coating

enlarged lymphatic vessel ( J:159519 )

• enlarged lymphatic vessels are even more dilated than in Tmem204^tm1.1Ali single knock-outs

muscle

abnormal lymphatic vessel smooth muscle morphology ( J:159519 )

• abnormal smooth muscle cell coating

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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