Phenotypes associated with this allele

• Allele Symbol: Coq4^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4441729
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Coq4^tm1a(EUCOMM)Wtsi/Coq4^tm1a(EUCOMM)Wtsi	C57BL/6N-Coq4^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5630987

Genotype
MGI:5630987

hm1

• Allelic Composition: Coq4^{tm1a(EUCOMM)Wtsi}/Coq4^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Coq4^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0498_3_C02

Data Sources

IMPC Data for Coq4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal chorion morphology ( J:261316 )

• unpatterned chorion at E9.5

abnormal placenta morphology ( J:261316 )

• branching morphology defect at E9.5

abnormal trophoblast layer morphology ( J:261316 )

• small or absent trophoblast compartment at E9.5

• biased differentiation (diploid/polyploid trophoblast)

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:261316 )

• complete lethality at E14.5

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI