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Allele Symbol Allele Name Allele ID |
Cdh23tm1.2Ugds targeted mutation 1.2, Unite de Genetique des Deficits Sensoriels MGI:4441515 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• absent from inner and outer hair cells at P5
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• absent from inner and outer hair cells at P5
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at P5, outer hair cell fold angle peaks at zero degrees indicating no detectable concavity unlike in wild-type mice
• the contour of the cuticular plate remains convex unlike in wild-type mice
• outer hair cells exhibit a slight flattening of their neural and abneural sides compared to in wild-type mice
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• hair bundles are fragmented compared to in wild-type mice
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• at P5, outer hair cell fold angle peaks at zero degrees indicating no detectable concavity unlike in wild-type mice
• the contour of the cuticular plate remains convex unlike in wild-type mice
• outer hair cells exhibit a slight flattening of their neural and abneural sides compared to in wild-type mice
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• hair bundles are fragmented compared to in wild-type mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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