All Phenotypes Nphp1<tm1Jgg> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nphp1^tm1Jgg
targeted mutation 1, Joseph G Gleeson
MGI:4437792

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nphp1^tm1Jgg/Nphp1^tm1Jgg	involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * NMRI	MGI:4437800
cn2	Ahi1^tm1Jgg/Ahi1^tm2.1Jgg Nphp1^tm1Jgg/Nphp1⁺ Tg(Pax6-cre,GFP)2Pgr/0	involves: 129 * C57BL/6 * FVB/N * NMRI	MGI:4437798
cx3	Ahi1^tm1Jgg/Ahi1⁺ Nphp1^tm1Jgg/Nphp1^tm1Jgg	involves: 129 * C57BL/6 * FVB/N * NMRI	MGI:4437801

Allelic Composition	Nphp1^tm1Jgg/Nphp1^tm1Jgg
Genetic Background	involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * NMRI

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nphp1^tm1Jgg mutation (1 available); any Nphp1 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

thin retina outer nuclear layer ( J:158019 )

• outer retinal thickness is reduced compared to in wild-type mice

retina degeneration ( J:158019 )

• at 2 months, mice exhibit slight retinal degeneration that progresses gradually

Allelic Composition	Ahi1^tm1Jgg/Ahi1^tm2.1Jgg Nphp1^tm1Jgg/Nphp1⁺ Tg(Pax6-cre,GFP)2Pgr/0
Genetic Background	involves: 129 * C57BL/6 * FVB/N * NMRI

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ahi1^tm1Jgg mutation (1 available); any Ahi1 mutation (80 available)
Ahi1^tm2.1Jgg mutation (1 available); any Ahi1 mutation (80 available)
Nphp1^tm1Jgg mutation (1 available); any Nphp1 mutation (26 available)
Tg(Pax6-cre,GFP)2Pgr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

thin retina outer nuclear layer ( J:158019 )

Allelic Composition	Ahi1^tm1Jgg/Ahi1⁺ Nphp1^tm1Jgg/Nphp1^tm1Jgg
Genetic Background	involves: 129 * C57BL/6 * FVB/N * NMRI

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ahi1^tm1Jgg mutation (1 available); any Ahi1 mutation (80 available)
Nphp1^tm1Jgg mutation (1 available); any Nphp1 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

thin retina outer nuclear layer ( J:158019 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23