Phenotypes associated with this allele

• Allele Symbol: Supt3^{tm1a(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:4435781
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Supt3^tm1a(EUCOMM)Hmgu/Supt3^tm1a(EUCOMM)Hmgu	C57BL/6N-Supt3^tm1a(EUCOMM)Hmgu/Wtsi	MGI:5701004

Genotype
MGI:5701004

hm1

• Allelic Composition: Supt3^{tm1a(EUCOMM)Hmgu}/Supt3^{tm1a(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Supt3^{tm1a(EUCOMM)Hmgu}/Wtsi
• Cell Lines: HEPD0527_5_F08

Data Sources

IMPC Data for Supt3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal chorion morphology ( J:261316 )

• unpatterned chorion at E9.5

abnormal placenta morphology ( J:261316 )

• branching morphology defect at E9.5

abnormal trophoblast layer morphology ( J:261316 )

• small or absent trophoblast compartment at E9.5

• biased differentiation (diploid/polyploid trophoblast)

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:261316 )

• complete lethality at E14.5

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI