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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Setd5tm1a(EUCOMM)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4432631
Summary 2 genotypes


Genotype
MGI:5631529
hm1
Allelic
Composition
Setd5tm1a(EUCOMM)Wtsi/Setd5tm1a(EUCOMM)Wtsi
Genetic
Background
C57BL/6N-Setd5tm1a(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0036_3_F05
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Setd5tm1a(EUCOMM)Wtsi mutation (1 available); any Setd5 mutation (54 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• unpatterned chorion at E9.5
• branching morphology defect at E9.5
• small or absent trophoblast compartment at E9.5
• biased differentiation (diploid/polyploid trophoblast)
• yolk sac abnormalities

mortality/aging




Genotype
MGI:5706088
ht2
Allelic
Composition
Setd5tm1a(EUCOMM)Wtsi/Setd5+
Genetic
Background
C57BL/6N-Setd5tm1a(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0036_3_F05
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Setd5tm1a(EUCOMM)Wtsi mutation (1 available); any Setd5 mutation (54 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

cardiovascular system

craniofacial

digestive/alimentary system

embryo

endocrine/exocrine glands

growth/size/body

hematopoietic system

homeostasis/metabolism

immune system

integument

liver/biliary system

muscle

nervous system

pigmentation

renal/urinary system

skeleton
IMPC - WTSI

vision/eye





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/01/2019
MGI 6.14
The Jackson Laboratory