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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kdrtm1.1Eia
targeted mutation 1.1, Anne Eichmann
MGI:4429911
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kdrtm1.1Eia/Kdrtm1.1Eia B6.129P2-Kdrtm1.1Eia MGI:4429913
cx2
 		Kdrtm1.1Eia/Kdr+
Nrp2tm1Ddg/Nrp2+ 		involves: 129P2/OlaHsd * C57BL/6 MGI:4429919


Genotype
MGI:4429913
hm1
Allelic
Composition		 Kdrtm1.1Eia/Kdrtm1.1Eia
Genetic
Background		 B6.129P2-Kdrtm1.1Eia
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdrtm1.1Eia mutation (0 available); any Kdr mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:156869 )
• homozygous mice die at early embryonic stages

cardiovascular system
abnormal vascular development ( J:156869 )
• failure of blood vessel formation




Genotype
MGI:4429919
cx2
Allelic
Composition		 Kdrtm1.1Eia/Kdr+
Nrp2tm1Ddg/Nrp2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdrtm1.1Eia mutation (0 available); any Kdr mutation (71 available)
Nrp2tm1Ddg mutation (0 available); any Nrp2 mutation (88 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:156869 )
N
• no obvious alteration in capillary density or patterning
• normal lymphatic vessel patterning and sprouting




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory