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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gt(ROSA)26Sortm1(RNU6-RNAi:Trpv1)Thch
targeted mutation 1, Thomas Christoph
MGI:4418115
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Gt(ROSA)26Sortm1(RNU6-RNAi:Trpv1)Thch/Gt(ROSA)26Sor+ Not Specified MGI:4418129


Genotype
MGI:4418129
ht1
Allelic
Composition
Gt(ROSA)26Sortm1(RNU6-RNAi:Trpv1)Thch/Gt(ROSA)26Sor+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(RNU6-RNAi:Trpv1)Thch mutation (0 available); any Gt(ROSA)26Sor mutation (504 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• capsaicin-treated mice exhibit less of a nocifensive response compared with similarly treated wild-type mice
• following spinal nerve ligation, mice fail to develop tactile hypersensitivity and allodynia unlike similarly treated wild-type mice

homeostasis/metabolism
• capsaicin-treated mice exhibit only short-lasting and mild body temperature reduction compared with similarly treated wild-type mice
• capsaicin-treated mice exhibit only short-lasting and mild body temperature reduction compared with similarly treated wild-type mice
• capsaicin-treated mice exhibit less of a nocifensive response compared with similarly treated wild-type mice

integument
• capsaicin-treated mice exhibit less of a nocifensive response compared with similarly treated wild-type mice
• following spinal nerve ligation, mice fail to develop tactile hypersensitivity and allodynia unlike similarly treated wild-type mice





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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory