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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Heyltm1.2Abmu
targeted mutation 1.2, Abhishek Mukhopadhyay
MGI:4365754
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Heyltm1.2Abmu/Heyltm1.2Abmu involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N MGI:4365768
cx2
 		Hey1tm1Gess/Hey1tm1Gess
Heyltm1.2Abmu/Heyltm1.2Abmu 		involves: 129 * C57BL/6 * FVB/N MGI:4365769
cx3
 		Hey1tm1Gess/Hey1tm1Gess
Heyltm1.2Abmu/Heyl+ 		involves: 129 * C57BL/6 * FVB/N MGI:4365772


Genotype
MGI:4365768
hm1
Allelic
Composition		 Heyltm1.2Abmu/Heyltm1.2Abmu
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Heyltm1.2Abmu mutation (0 available); any Heyl mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased sensory neuron number ( J:153555 )
• TrkC+ sensory neurons are reduced 19% in the dorsal root ganglia compared to in wild-type mice




Genotype
MGI:4365769
cx2
Allelic
Composition		 Hey1tm1Gess/Hey1tm1Gess
Heyltm1.2Abmu/Heyltm1.2Abmu
Genetic
Background		 involves: 129 * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hey1tm1Gess mutation (0 available); any Hey1 mutation (17 available)
Heyltm1.2Abmu mutation (0 available); any Heyl mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:153555 )
N
• mice exhibit normal numbers of TrkC+ sensory neurons in the dorsal root ganglia




Genotype
MGI:4365772
cx3
Allelic
Composition		 Hey1tm1Gess/Hey1tm1Gess
Heyltm1.2Abmu/Heyl+
Genetic
Background		 involves: 129 * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hey1tm1Gess mutation (0 available); any Hey1 mutation (17 available)
Heyltm1.2Abmu mutation (0 available); any Heyl mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
increased sensory neuron number ( J:153555 )
• mice exhibit an increased in the number of TrkC+ sensory neurons in the dorsal root ganglia compared with wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory