Phenotypes associated with this allele

• Allele Symbol: Gper1^tm1Dgen
• Allele Name: targeted mutation 1, Deltagen
• Allele ID: MGI:4355679
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gper1^tm1Dgen/Gper1^tm1Dgen	B6.129-Gper1^tm1Dgen	MGI:4355680

Genotype
MGI:4355680

hm1

• Allelic Composition: Gper1^tm1Dgen/Gper1^tm1Dgen
• Genetic Background: B6.129-Gper1^tm1Dgen

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased T cell number ( J:151816 )

• mice exhibit a decrease in CD45+ T cells in peripheral blood leukocytes compared with wild-type mice

decreased CD4-positive, alpha-beta T cell number ( J:151816 )

• decreased 25% in females and 30% in males

decreased CD8-positive, alpha-beta T cell number ( J:151816 )

• decreased 21% in females and 28% in males

growth/size/body

growth/size/body region phenotype ( J:151816 )

N • mice exhibit normal body weight and composition even when fed a high fat diet

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:151816 )

N • mice exhibit normal glucose tolerance

hematopoietic system

decreased T cell number ( J:151816 )

• mice exhibit a decrease in CD45+ T cells in peripheral blood leukocytes compared with wild-type mice

decreased CD4-positive, alpha-beta T cell number ( J:151816 )

• decreased 25% in females and 30% in males

decreased CD8-positive, alpha-beta T cell number ( J:151816 )

• decreased 21% in females and 28% in males