About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rapgef4Gt(OST450264)Lex
gene trap OST450264, Lexicon Genetics
MGI:4321519
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rapgef4Gt(OST450264)Lex/Rapgef4Gt(OST450264)Lex 129S5/SvEvBrd-Rapgef4Gt(OST450264)Lex MGI:5304300


Genotype
MGI:5304300
hm1
Allelic
Composition		 Rapgef4Gt(OST450264)Lex/Rapgef4Gt(OST450264)Lex
Genetic
Background		 129S5/SvEvBrd-Rapgef4Gt(OST450264)Lex
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rapgef4Gt(OST450264)Lex mutation (1 available); any Rapgef4 mutation (64 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal calcium ion homeostasis ( J:179540 )
• Calcium-induced Ca2+ release induced by cAMP elevating agents is either reduced or lost in pancreatic beta cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory