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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
CicGt(XE565)Byg
gene trap XE565, BayGenomics
MGI:4125985
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
CicGt(XE565)Byg/CicGt(XE565)Byg involves: 129P2/OlaHsd * C57BL/6J MGI:5301624
ht2
CicGt(XE565)Byg/Cic+ B6.129P2-CicGt(XE565)Byg MGI:5297805
cx3
Atxn1tm1Hzo/Atxn1+
CicGt(XE565)Byg/Cic+
B6.129-CicGt(XE565)Byg Atxn1tm1Hzo MGI:5297806


Genotype
MGI:5301624
hm1
Allelic
Composition
CicGt(XE565)Byg/CicGt(XE565)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CicGt(XE565)Byg mutation (1 available); any Cic mutation (69 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• most die before weaning

growth/size/body
• some survivors are smaller than wild type littermates

respiratory system
• severe alveolarization defects




Genotype
MGI:5297805
ht2
Allelic
Composition
CicGt(XE565)Byg/Cic+
Genetic
Background
B6.129P2-CicGt(XE565)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CicGt(XE565)Byg mutation (1 available); any Cic mutation (69 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• mice exhibit normal survival

behavior/neurological
N
• mice exhibit normal activity, motor coordination, and fear conditioning




Genotype
MGI:5297806
cx3
Allelic
Composition
Atxn1tm1Hzo/Atxn1+
CicGt(XE565)Byg/Cic+
Genetic
Background
B6.129-CicGt(XE565)Byg Atxn1tm1Hzo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atxn1tm1Hzo mutation (1 available); any Atxn1 mutation (29 available)
CicGt(XE565)Byg mutation (1 available); any Cic mutation (69 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• not as severe as in Atxn1tm1Hzo homozygotes

nervous system
N
• mice exhibit improved Purkinje cell count compared with Atxn1tm1Hzo homozygotes
• as in Atxn1tm1Hzo homozygotes

behavior/neurological
N
• mice exhibit improved activity, coordination, and fear conditioning compared with Atxn1tm1Hzo homozygotes

growth/size/body
N
• weight loss observed in Atxn1tm1Hzo homozygotes is rescued





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory