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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ift80Gt(AN0245)Wtsi
gene trap AN0245, Wellcome Trust Sanger Institute
MGI:3856827
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ift80Gt(AN0245)Wtsi/Ift80Gt(AN0245)Wtsi involves: 129P2/OlaHsd MGI:4942392


Genotype
MGI:4942392
hm1
Allelic
Composition
Ift80Gt(AN0245)Wtsi/Ift80Gt(AN0245)Wtsi
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ift80Gt(AN0245)Wtsi mutation (0 available); any Ift80 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected mice are present at P0
• fewer than expected mice are present at P0

skeleton
• flattened in the anterior posterior axis
• the hypertrophic chondrocyte zone is poorly organized and smaller than in wild-type mice
• shortening is slightly more severe in distal rather than proximal limb elements
• ribs exhibit an irregular margin between bone and cartilage compared with wild-type mice
• thoracic cages are constricted compared to in wild-type mice

limbs/digits/tail
• bilateral in hind limbs with a single extra digit longer than other digits

growth/size/body
N
• mice exhibit normal sidedness, indicating normal ciliary function

renal/urinary system
N
• at P21, mice exhibit normal kidney morphology

vision/eye
N
• at P21, mice exhibit normal retina layers

craniofacial
• flattened in the anterior posterior axis





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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory