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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Akt3tm1Nhy
targeted mutation 1, Nissim Hay
MGI:3848061
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Akt1tm1Nhy/Akt1+
Akt2tm1Rsg/Akt2tm1Rsg
Akt3tm1Nhy/Akt3tm1Nhy
involves: 129/Sv * C57BL/6 * DBA/1LacJ MGI:3848164
cx2
Akt2tm1Rsg/Akt2tm1Rsg
Akt3tm1Nhy/Akt3tm1Nhy
involves: 129/Sv * C57BL/6 * DBA/1LacJ MGI:3848166


Genotype
MGI:3848164
cx1
Allelic
Composition
Akt1tm1Nhy/Akt1+
Akt2tm1Rsg/Akt2tm1Rsg
Akt3tm1Nhy/Akt3tm1Nhy
Genetic
Background
involves: 129/Sv * C57BL/6 * DBA/1LacJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Akt1tm1Nhy mutation (0 available); any Akt1 mutation (24 available)
Akt2tm1Rsg mutation (0 available); any Akt2 mutation (25 available)
Akt3tm1Nhy mutation (0 available); any Akt3 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism




Genotype
MGI:3848166
cx2
Allelic
Composition
Akt2tm1Rsg/Akt2tm1Rsg
Akt3tm1Nhy/Akt3tm1Nhy
Genetic
Background
involves: 129/Sv * C57BL/6 * DBA/1LacJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Akt2tm1Rsg mutation (0 available); any Akt2 mutation (25 available)
Akt3tm1Nhy mutation (0 available); any Akt3 mutation (8 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice exhibit a diabetic phenotype similar to Akt2tm1Rsg homozygotes





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory